Decoding Tissue Immunity
Through Data and AI
At ImmSilico, we believe the future of immune health lies at the intersection of groundbreaking experimental science and transformative technologies. As a specialist consultancy, we guide innovation in immunology by leveraging artificial intelligence, advanced data analytics, and cutting-edge experimental platform like single cell and spatial technologies.
Our mission is to help to decode tissue immunity — unlocking its potential to prevent and treat diseases through data-driven discovery and technology enabled solutions.
Why ImmSilico?
At ImmSilico, we sit at the intersection of immunology, artificial intelligence, and experimental innovation.
Our expertise goes beyond analytics — we help decode the *principles* that drive tissue-level immune responses.
We’re not just analysts — we’re co-thinkers.
Our consultancy empowers researchers and teams to design better experiments, ask deeper questions, and uncover insights that matter.
From single-cell platforms to interpretable models, we guide every step with clarity, strategy, and scientific integrity.
What We Do
Experimental Strategy
Plan powerful, feasible studies using the latest single-cell and spatial platforms.
AI & Data for Immunity
Unlock insight from immune datasets with interpretable, custom-built models.
Integrated Data Design
Connect experimental, clinical, and public data streams to answer complex biological questions.
Testimonials/ Client Feedback
“Trusted by Scientists, Loved by Innovators”
Impact Stories
Tracking In Situ Checkpoint Inhibitor-Bound Target T Cells in Patients with Checkpoint-Induced Colitis (Cancer Cell 2024)
Our involvement in this study focused on tracking T cells bound by checkpoint inhibitors in patients experiencing checkpoint inhibitor-induced colitis. Utilizing advanced imaging and molecular techniques, we identified the presence and behaviour of these T cells within intestinal tissues, contributing to a better understanding of immune-related adverse events and informing strategies to mitigate such complications in cancer immunotherapy.
singe-cell Atlas of Colonic CD8+ T Cells in Ulcerative Colitis (Nature Medicine, 2020)
Our team collaborated on constructing a comprehensive single-cell atlas of colonic CD8⁺ T cells in both healthy individuals and those with ulcerative colitis (UC). By employing single-cell RNA sequencing, we identified distinct T cell subsets and their functional states, providing deeper insights into the immunological landscape of the colon in UC. This work enhances our understanding of disease mechanisms and may inform the development of targeted therapies for UC.
Spatiotemporal Analysis of Human Intestinal Development at Single-Cell Resolution (Cell 2020)
In collaboration with leading researchers, we conducted a comprehensive analysis of human intestinal development using single-cell RNA sequencing and spatial transcriptomics. This study provided a detailed map of intestinal morphogenesis, identifying 101 distinct cell states and offering insights into the formation of the crypt-villus axis, as well as neural, vascular, and immune development within the gut.
Book a Free Call
Ready to transform how your team understands immunity?